Department of Biochemistry strives to inculcating the culture of state of an art Diagnostic Laboratory .It has a autoanalyser ,ABG machine, Electrolyte Analyser. The academic block houses the Biochemistry Department in one of the wings of Gautam Buddha University.The department is well equipped for undergraduate MBBS ,MSc Biochemistry etc. Department of Biochemistry strives to inculcate the culture of state of an art diagnostic Laboratory .It houses an autoanalyser ,ABG machine, Electrolyte Analyser,HbA1C analyser and other accessories.A plethora of tests,soon to be added is in the pipeline.It has a Research Lab in the diagnostic wing where special tests in genomics and proteomics will soon be available.

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Mission

Establishment of Inborn Errors of Metabolism Lab

Establishment of Molecular Laboratory, Genomics and Proteomics Lab (SNPs, Telomerase study, cloning, Sequencing)

Bio markers in in non communicable disease, encompassing Metabolic Syndrome and Preeclampsia/eclampsia

Eg FFA, Endothelin, cytokines, oxidative stress parameters, TTR

Cardiovascular Laboratory

Year of Establishment - 2017

Name of the first HOD

Dr. Vanita lal (Professor)
MBBS (Honours), MD (Biochemistry), DNBE, MNAMS, FAIMER Fellow
CMS GIMS

Names & Qualification of all members

Dr. Manisha Singh
MD
Associate Professor

Dr. Mamta Padhy
MD
Assistant Professor

Dr.Kulbhushan Tyagi
MBBS
Tutor

Dr.Karli Sreenivasulu
M Sc(MEDICAL BIOCHEMISTRY),Ph.D
Tutor

MR.Ravoori Saideswar Rao
M Sc (MEDICAL BIOCHEMISTRY)
Tutor

She graduated (MBBS) from the prestigious Institution ,Patna Medical College and Hospital (Initially called Prince of Wales Medical College) where she was a scholar with distinction holder. She did her post graduation (MD)from Rajendra Institute Of Medical Sciences(initially RMCH) Ranchi and moved to JIPMER ,Pondicherry to pursue her Senior Residency in Biochemistry.She holds the degree of Diplomate of National Examination from AFMC(Pune).She got selected in Central Government jobs in Central Institute Of Psychiatry ( GoI) and then moved to her Alma mater .Later she joined as founder faculty group as Associate Professor in the department of Biochemistry after her selection in All India Institute of Medical Sciences, Jodhpur Rajasthan through MoHFW . She was an elected member at National Academy of Medical Sciences, New Delhi. She has keen interest in medical education & obtained FAIMER Fellowship from CMC Ludhiana.She has been a research associate with NRHM project in RIMS,Ranchi,. She has many national and international publications to her credit and has presented papers in country and overseas. Apart from life membership of national scientific forums viz ACBI, AMBI, NAMS, NMO, ISMG,InSLAR, She is a life time member of International Society of Inborn Errors of Metabolism, American Association of Clinical Chemistry , overseas member of Australian Association of Clinical Biochemist and South East Asian Association of Research in Medical Education (SEARME) She has chaired various scientific sessions in academic events in India and abroad .She was invited guest speaker in the University of Pretoria recently. She is heading the Department of Biochemistry at GIMS,Greater Noida with the additional charge of Chief Medical Superintendent .

Details Research projects completed in 2007 and currently undertaken in Department by Dr. Vanita Lal

1. Completed ICMR STS project 2013: Reference NO. No.2013-04095 Title: Comparative study of Laboratory Indices of Gym trainees, Athletes and Normal controls. Certificate received from ICMR.
2. Health indices in cotton mill workers in Buhranpur as .Co investigator (Funded by The Union, IUATLD, New Delhi). 2013 completed . Buhranpur Byssinosis project:
3. A prospective study to screen encephalopathic neonates for Hyperammonemia with or without metabolic acidosis. Intramural Project:1
4. ICMR STS 2015: is Profiling Urinary Amino Acids and Monosaccharides by Thin Layer Chromatography in Paediatric subjects with suspected metabolic disorders. ( Ref ID 2015-04064)
5. FAIMER 2015 Project on Medical Education: Team Based Learning (TBL) by Modular Teaching - Reinvigorating Second Semester MBBS Students at AIIMS, Jodhpur
6. 7.2nd Intramural Project: Transthyretin (TTR): Its possible Role in Depression in Subclinical Hypothyroids & Euthyroids Undergoing Routine Thyroid Profiling
7. Ongoing: Utility of the product of calcium and phosphorus [Serum ionised Calcium X Inorganic Phosphate] in relation to Lipid Sub Fractions in Predialysed Chronic Kidney Disease (CKD): Ongoing Non funded
8. Sympathetic tone and its relation with endothelial function and left ventricular diastolic function in hypertensive patients. Intramural Project. Co-Investigator with Faculty of Physiology,AIIMS,Jodhpur.

Submitted proposals by Dr. Vanita Lal

1. Extramural: Submitted in July 2016, As concept note Submitted For DBT-ICMR Collaborative effort on Maternal and Child Health (Advt. No. BT/Med-II/ JWG-MCH-Advt/2016 (Government of India) Title: Exploration of gene polymorphism from the vascular perspective & extrapolation to circulating markers in patients of early onset preeclampsia.
2. ICMR STS 2017 for Review at Institute Research Cell: Measurement of Urinary Sodium, Urinary Osmolality and its association with Systolic Blood Pressure in recent cases of Hypertension yet to commence any drug regimen.

Details of Research publications and chapters published by Dr. Vanita Lal

1. Lal.V,Gupta G,Journal of Clinical and diagnostic 1.Research: A case of hyperargininaemia presenting at unusually low age, Aug,2017) PubMed Indexed
2. Vanita Lal, Praveen Sharma, Purvi Purohit. Metabolic Syndrome in Pediatric Age group, a group requiring review. International Journal of Obesity and Metabolic Research, [2014]; [Vol 1] [238-245]
3. Vanita Lal,Bharti Bhandari,Anubhav R. Chronic Effects of Aerobic and Resistance Exercise on Cardio Metabolic Profile in Healthy Non Obese Subjects. 2014; International journal of clinical & experimental physiology [3][200-205]
4. Vanita Lal,Bharti Bhandari. Protective Role of Ascorbic Acid in Hemorrhage Induced Cardiovascular Depression. Indian Journal Physiology and Pharmacology. 2014; 58[4][1-6] Pubmed indexed
5. Vanita Lal,A.Das , Metabolic Syndrome &Obesity in Children , The Global Health Action.[ Vol 27 ],[10-24] Non PubMed Indexed
6. Vanita L, A.Das. A Das .MDR Tb:Global Changing Paradigm : diagnosis and management . Health Action 2015 [2][4-7] Non Indexed
7. Vanita L. Merits and demerits of Hemoglobin Electrophoresis subtypes over Reverse phase HPLC. Journal of Clinical and Scientific Research, Supplement. 10/2014; 3[4].
8. A Das,Thapa B,Vanita L , Prevalence of Byssinosis amongst home-based power loom workers in MP, India International Journal of Tuberculosis and Lung Disease. Submitted. Under review.
9. Vanita Lal Das,Small group discussion followed by presentation as a revision exercise at the end of amino acid metabolism module. National Medical Journal of India: Published .Vol 17, no.1, 2004.Pubmed Indexed
10. Indian Journal of Pathology & Microbiology: The Congenital Afibrinogenemia diagnosis by estimating plasma fibrinogen by conventional method with clinical correlation. .Published.51 (2), April-June2008.Pubmed Indexed
11. Metabolic Syndrome &Obesity in Children [No 4-8],Vol 27 The Health Action April-Aug-2 Volumes.Pg,10-24.
12. Feedback assessment for Team Based Learning : Sent to Journal of Education and Health Promotion,Oct.2016
13. Vanita L, Bharti Praveen S Team Based Learning (TBL) Reinvigorating interest in Biochemistry among undergraduate medical Students sent to J of Educational Evaluation for Health Prof. 2017 Jan
14. V. Lal, V Singh, P.Sharma High Fructose to Glucose Ratio in diet is deleterious to Health ,Abstract book of CME on Diabetes:High time to act. International Epidemiological Association.7-9April, 2016.
15. Serum Gamma Glutamyl Transferase activity in Patients with Cardiovascular Disease Associated with DM. Manuscript No. EJPMR/5362/2018 European Journal of Pharmaceutical and Medical Research.
16. .Role of Myoinositol in Reducing Insulin Resistance in PCOS patients submitted to JEMDS,Journal of Evolution of Medical ANS
17. Role of Blood Transthyretin ( TTR) in Euthyroid patients with Depression A pilot study .Submitted to JEMDS

Details of national & international awards won by Dr. Vanita Lal

1. Guest Speaker at University of Pretoria ,South Africa: on Laboratory tests on MDR and XDR Tuberculosis.October 27th 2017.

Resource Person/ Chairperson

1. Biochemical Diagnosis of Infectious Diseases Dr.S. Senthil Kumaran Guest Speaker at AMBICON 2014
2. Chaired two sessions in IPHACON Feb 24, 2017
3. Judged the poster competition at IPHACON Feb 25, 2017

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Dr Manisha Singh is Associate professor in department of Biochemistry

Details of Research publications and chapters published by Dr Manisha Singh

1. Manisha Singh, Eqbal Anwar, Vishnu Kumar. Assessment of biochemical parameters in the patients of coronary artery disease with Type 2 Diabetes Mellitus. International Journal of Pharmaceutical Sciences and Research(2017); Vol8, Issue 3
2. Asfia Khan, BrijeshRathore, Manisha Singh,Aparna Misra. Association of creatine kinase and its isoenzymes(CK-MB, CK-BB) activity with high risk pregnancy. International Journal of Research in Medical Sciences. 2017, Apr;5(4):1464-1470
3. Aparna Misra, Manisha Singh, Anchal Trivedi, Brijesh Singh Rathore, Anil K. Balapure. In-vitro effect of Picroliv on Plasmodium Berghei Induced Alterations in the Activity of Adenosine Triphosphatase, Aryl Hyrocarbon Hydroxylase Enzymes and MDA in Liver Explant Culture. Indian Journal of Pathology Research and Practice, Volume 5 Number 2, May-August 2016.
4. Manisha Singh, IpsitaChoudhary, VasanthiPallinti, R Jothimalar, Visnhu Kumar and Aparna Misra. Association between PRO12ALA polymorphism at the PPAR?2 gene and insulin sensitivity in South Indian population with type-2 diabetes mellitus. Indian Journal of Basic and Applied Medical Research; June 2016: Vol-5, Issue-3, P. 722-741
5. BrijeshRathore, Manisha Singh, Vishnu Kumar, and Aparna Misra. Osteocalcin: An Emerging Biomarker for Bone Turnover. International Journal of Research in Medical Sciences (2016) 4 (9): 3670-3674.
6. Vishnu Kumar, RituKaroli, Manisha Singh, Aparna Misra and Farzana Mahdi. Evaluation of Oxidative Stress, Antioxidant Enzymes, Lipid and Lipoprotein Profile in Type-2 Diabetic Patients. International Journal of Bioassays: September 6, 2015; Accepted: September 25, 2015
7. Vishnu Kumar, Farzana Mahdi, Ranjana Singh, Abbas Ali Mahdi, Kalbe Jawad, Raj Kumar Singh and Manisha Singh (2015). Cassia Tora Seeds Extract Regulates Lipid Metabolism in Alloxan Induced Diabetic Rats. International Journal of Pharmacology Science and Research Vol. 6(8): 3484-3489.
8. RichaGupta, Manisha Singh, JibhateAnirudha, Mahdi Farzana.Novel Methodology for Implementation of OSCE as Examination Tool to Delimit Space and Time Constraints. Journal of Medical Education& Research, Vol 3, No.1,Jan June 2013

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Dr. Mamta Padhy is Assistant professor in department of Biochemistry

Details of Research publications and chapters published by Dr. Mamta Padhy

1. Serum Netrophil Gelatinase Associated Lipocalin(NGAL) and Cystatin C) as early predictors of Contrast-Induced Acute Kidney Injury in patients undergoing percutaneous coronary Clinica Chimica Acta 435 (2014) 48-52.
2. Correlation of oxidative stress biomarker and serum marker of brain injury in hypoxic ischemic encephalopathy International Journal of Medical & Applied Sciences,Volume 3,Issue 1,2014
3. Procalcitonin and C-reactive protein in early diagnosis of neonatal sepsis Indian Joutnal of Medical Specialities.Print-0976-2884.Online-0976-2892

Details of national & international awards won by Dr. Mamta Padhy

1. Prize in Poster Presentation titled NGAL and Cystatin C (Serum Netrophil Gelatinase Associated Lipocalin and Cystatin C) as early predictors of Contrast-Induced Acute Kidney Injury in patients undergoing percutaneous coronary intervention. at 40th National Conference of Association of Clinical Biochemists of India(ACBICON 2013) held at New Delhi.

Facility available in Department with capacity

Equipments available:

Biochemistry Laboratory (Central Laboratory)
Selectra Pro M (fully automated routine chemistry analyzer) POCT
Chemilumincent (Architect I 1000 SR) POCT
Emergency Laboratory
Selectra ProS(fully automated routine chemistry analyzer) POCT
Inolyte -- POCT
Semi auto analyzer
ABG analyzer

Teaching Aids available

LCD (2)
TV (2)
OVERHEAD PROJECTER (2)
Computer(1)

New Facilities / improvements made

Extension of Clinical biochemistry Laboratory
Emergency laboratory